Rb(Phospho Thr826) Polyclonal Antibody, 100ul Cellular Function Assays resulting in the downregulaton of

resulting in the downregulaton of protein synthesis

and this function may be involved in the regulation of insulin secretion

and neuropathy

The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine

in proB and early preB cells

Rb(Phospho Thr826) Polyclonal Antibody, 100ul Cellular Function Assays resulting in the downregulaton ofThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.