PU.1 Polyclonal Antibody, 50ul Cell Senescence Mutations in this gene cause
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PU.1 Polyclonal Antibody, 50ul Cell Senescence Mutations in this gene causeSPI1 encodes an ETS domain transcription factor that activates gene expression during myeloid and B lymphoid cell development. The nuclear protein binds to a purine rich sequence known as the PU box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. Spi 1 proto oncogene can also regulate alternative splicing of target genes. Multiple transcript variants encoding
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