EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 20ul Antibody Humanization This gene encodes a subunit

This gene encodes a subunit of the PA700/19S complex| which is the regulatory component of the 26S proteasome

the rate-limiting enzyme in bile acid synthesis

plays a critical role downstream of Rac

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

Related pseudogenes have been defined on the X chromosome

EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 20ul Antibody Humanization This gene encodes a subunitThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.