3BHS1 Polyclonal Antibody, 50ul Shakers NUMA1 encodes a large protein

NUMA1 encodes a large protein that forms a structural component of the nuclear matrix

This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex

subcellular location:Shows a cytoplasmic localization when co-expressed with MAP3K12

which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates

PTM:Phosphorylated by GSK3B

3BHS1 Polyclonal Antibody, 50ul Shakers NUMA1 encodes a large proteinThe protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta 5 3 beta hydroxysteroid precursors into delta 4 ketosteroids which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3 beta hydroxy and 3 keto 5 alpha androstane steroids.