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CD32-C Polyclonal Antibody, 100ul Molecular Sciences Calcineurin like EF-hand protein 2

SKU: 61989254789

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CD32-C Polyclonal Antibody, 100ul Molecular Sciences Calcineurin like EF-hand protein 2FCGR2C (Fc fragment of IgG receptor IIc (gene pseudogene)) encodes one of three members of a family of low affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in FCGR2C results in both coding and non coding variants.

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Description

Calcineurin like EF-hand protein 2 shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway

The family includes secreted and membrane-associated proteins

As the encoded protein has not been detected

however| it may be involved in aspects of immunosuppression

Mutations in this gene cause hyperlipoproteinemia type IB

CD32-C Polyclonal Antibody, 100ul Molecular Sciences Calcineurin like EF-hand protein 2FCGR2C (Fc fragment of IgG receptor IIc (gene pseudogene)) encodes one of three members of a family of low affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in FCGR2C results in both coding and non coding variants.

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