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DIRA3 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Type 1 alternative splice variants

SKU: 62205676339

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DIRA3 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Type 1 alternative splice variantsThis gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.

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Description

Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8

It also interacts with multiple proteins including calmodulin| CABP1| enkurin| Na(+)-H+ exchange regulatory factor (NHERF )| interferon-induced GTP-binding protein (MX1)| ring finger protein 24 (RNF24)| and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

which is a subcomplex of the dystrophin-glycoprotein complex (DGC)

Upon tyrosine phosphorylation

ANX4 encodes a protein that has possible interactions with ATP

DIRA3 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Type 1 alternative splice variantsThis gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.

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