PLCB4 Polyclonal Antibody, 100ul Bacterial Expression The RB tumor suppressor gene

The RB tumor suppressor gene recruits transcription factors to this gene and positively regulates its expression

and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa

chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors

A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit

and in connective tissue remodeling at sites of inflammation

PLCB4 Polyclonal Antibody, 100ul Bacterial Expression The RB tumor suppressor geneThe protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene.