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CI072 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Amplification This zinc finger gene has

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CI072 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Amplification This zinc finger gene hasThe protein encoded by this gene plays an important role in the regulation of endosomal trafficking, and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport. Expansion of a GGGGCC repeat from 2 22 copies to 700 1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia)

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Description

This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma

and are mitogens for several cell types

Three genes encoding alpha

Low BMD is a risk factor for osteoporotic fracture

The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C)

CI072 Rabbit Polyclonal Antibody, 50ul Nucleic Acid Amplification This zinc finger gene hasThe protein encoded by this gene plays an important role in the regulation of endosomal trafficking, and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport. Expansion of a GGGGCC repeat from 2 22 copies to 700 1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia)

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