SPAK Polyclonal Antibody, 100ul[BT-AP08490] DNA Fragments Some of these isoforms may

Some of these isoforms may undergo similar processing to generate the mature peptide

and regulate the activity of numerous protein kinases of the JNK signaling pathway

It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome

Binds ARHGEF11

This gene along with four other members of the interleukin 1 receptor family

SPAK Polyclonal Antibody, 100ul[BT-AP08490] DNA Fragments Some of these isoforms maySTK39 encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the