BLNK Polyclonal Antibody, 50ul Live Cell Imaging Cystic fibrosis transmembrane conductance regulator

Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene

A chromosomal translocation involving this gene and the IgH locus

The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis

All variants share the N-terminal region in common

subcellular location:In ejaculated spermatozoa

BLNK Polyclonal Antibody, 50ul Live Cell Imaging Cystic fibrosis transmembrane conductance regulatorBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia