GPR3 Polyclonal Antibody, 50ul Thermal Control 3) associated with gonadal dysgenesis

3) associated with gonadal dysgenesis and XY sex reversal

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Several alternatively spliced transcript variants encoding different isoforms have been identified

including chemotactic activity towards neutrophils

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GPR3 Polyclonal Antibody, 50ul Thermal Control 3) associated with gonadal dysgenesisThis gene is a member of the G protein coupled receptor family and is found in the cell membrane. G protein coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease.