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CPA1 Polyclonal Antibody, 100ul Biomatrix The introduction of DAP kinase

SKU: 63186452570

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SEK123.75 SEK149.75

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CPA1 Polyclonal Antibody, 100ul Biomatrix The introduction of DAP kinaseThis gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C terminal branched chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.

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Description

The introduction of DAP kinase into highly metastatic carcinoma clones lacking DAP kinase expression was shown to result in the suppression of metastasis

This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity

Phosphorylates and activates MAP2K4 and MAP2K6| which in turn activate the JNK and p38 MAP kinases| respectively

Mediates cell-cell adhesion in a calcium-dependent manner (By similarity)

Gene Ontology (GO) annotations related to POU3F1 include transcription factor activity

CPA1 Polyclonal Antibody, 100ul Biomatrix The introduction of DAP kinaseThis gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C terminal branched chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer.

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