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MDM1 Polyclonal Antibody, 50ul Plasma cAMP-dependent phosphorylation of proteins by

SKU: 63407194256

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MDM1 Polyclonal Antibody, 50ul Plasma cAMP-dependent phosphorylation of proteins byMDM1 (Mdm1 nuclear protein) encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for MDM1.

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Description

cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes| including differentiation| proliferation| and apoptosis

which are a subset of the Ste20-like kinases

subcellular location:Colocalizes with endosomes

this gene may play a role in the Down Syndrome phenotype

Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells

MDM1 Polyclonal Antibody, 50ul Plasma cAMP-dependent phosphorylation of proteins byMDM1 (Mdm1 nuclear protein) encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for MDM1.

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