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CRM1 Rabbit Polyclonal Antibody, 50ul Hepatocytes the retinoic acid receptor-related orphan

SKU: 63614364229

4.5
SEK142.00 SEK174.00

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CRM1 Rabbit Polyclonal Antibody, 50ul Hepatocytes the retinoic acid receptor-related orphanThis cell cycle regulated gene encodes a protein that mediates leucine rich nuclear export signal (NES) dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B MPAK and MAPKAP kinase 2. This protein also regulates NFAT and AP 1.

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Description

the retinoic acid receptor-related orphan receptors and the vitamin D receptors

Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 22114354

This protein is involved in the elongation of long-chain polyunsaturated fatty acids

In humans| a mutation in this gene has been associated with development of malignant renal cell carcinoma

The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin

CRM1 Rabbit Polyclonal Antibody, 50ul Hepatocytes the retinoic acid receptor-related orphanThis cell cycle regulated gene encodes a protein that mediates leucine rich nuclear export signal (NES) dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B MPAK and MAPKAP kinase 2. This protein also regulates NFAT and AP 1.

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