IRS-1 Polyclonal Antibody, 50ul[BT-AP04642] Buffers & Solutions Members of the Ikaros (ZNFN1A1

Members of the Ikaros (ZNFN1A1

Barely detectable in liver

The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas

This gene has been found to be rearranged| mutated| or amplified in a series of tumours including anaplastic large cell lymphomas| neuroblastoma| and non-small cell lung cancer

The protein is involved in repressing and activating a diverse number of promoters

IRS-1 Polyclonal Antibody, 50ul[BT-AP04642] Buffers & Solutions Members of the Ikaros (ZNFN1A1IRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.