CYTS Polyclonal Antibody, 100ul Molecular Biology Regulates transcription from the PADI1

Regulates transcription from the PADI1 and CDH2 promoter

A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation

it is thought that the presenilins are involved in the cleavage of the Notch receptor

Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner

Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome)

CYTS Polyclonal Antibody, 100ul Molecular Biology Regulates transcription from the PADI1The cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a