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SCP-2 Polyclonal Antibody, 50ul DNA Fragments Two uORFs in the 5'

SKU: 64108942306

4.3
SEK162.00 SEK212.00

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SCP-2 Polyclonal Antibody, 50ul DNA Fragments Two uORFs in the 5'The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. Synaptonemal complex protein 2 encoded by SYCP2 is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.

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Description

Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein

May play an important role in the pathogenesis of neurogenetic diseases

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|Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity

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SCP-2 Polyclonal Antibody, 50ul DNA Fragments Two uORFs in the 5'The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. Synaptonemal complex protein 2 encoded by SYCP2 is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.

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