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Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIP

SKU: 64163753395

4.7
USD141.00 USD177.00

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Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIPShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

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Description

The protein encoded by VIP (vasoactive intestinal peptide) belongs to the glucagon family

a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif

RUNX proteins form a heterodimeric complex with CBFβ which confers increased DNA binding and stability to the complex

NCAPG (non-SMC condensin I complex subunit G) encodes a subunit of the condensin complex

and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B

Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIPShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

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