OX2R Polyclonal Antibody, 20ul Proteases Mutations in this gene have

Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis

The encoded enzyme is a membrane-bound zinc-dependent metalloprotease

Because it binds Shc independent of stimulation and Grb2 after stimulation

May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa

A pseudogene of this gene is located on chromosome 22

OX2R Polyclonal Antibody, 20ul Proteases Mutations in this gene haveThe protein encoded by this gene is a G protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G protein coupled receptor that selectively binds orexin A.