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GCH1 Polyclonal Antibody, 50ul Cell Biology which includes SIN3

SKU: 6443928082

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PLN185.00 PLN223.00

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GCH1 Polyclonal Antibody, 50ul Cell Biology which includes SIN3This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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Description

which includes SIN3

It is preferentially associated with mRNAs produced by splicing| including both nuclear mRNAs and newly exported cytoplasmic mRNAs

Mutations in this gene cause epidermolytic palmoplantar keratoderma

An important paralog of RAB6C is RAB41

G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits

GCH1 Polyclonal Antibody, 50ul Cell Biology which includes SIN3This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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