MDR3 Polyclonal Antibody, 100ul Reagent Reservoirs Defects in this gene are

Defects in this gene are the cause of Werner syndrome| an autosomal recessive disorder characterized by premature aging

cerebral and renal blood flow

Alternative splicing of this gene results in two transcript variants

neuronal growth cone collapse and cell migration

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2)| as a result of transcription initiation from 2 independently regulated promoters

MDR3 Polyclonal Antibody, 100ul Reagent Reservoirs Defects in this gene areThe membrane associated protein encoded by this gene is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR TAP subfamily. Members of the MDR TAP subfamily are involved in multidrug resistance as well as antigen