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p47-phox Polyclonal Antibody, 50ul[BT-AP06793] Miscellaneous It is a predominantly cytoplasmic

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p47-phox Polyclonal Antibody, 50ul[BT-AP06793] Miscellaneous It is a predominantly cytoplasmicThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.

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Description

It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines

lymph nodes and thymus

the major microtubule-organizing centers of animal cells

miscellaneous:2 N-termini have been observed in the mature protein: the first at Glu-30

This gene is a susceptibility locus for schizophrenia and bipolar disorder

p47-phox Polyclonal Antibody, 50ul[BT-AP06793] Miscellaneous It is a predominantly cytoplasmicThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.

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