ANF Polyclonal Antibody, 50ul PCR Series juvenile myoclonic epilepsy (JME)

juvenile myoclonic epilepsy (JME)

This member is a predominantly cytoplasmic protein

is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain

Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain| although some members contain only the sterol-binding domain

It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters

ANF Polyclonal Antibody, 50ul PCR Series juvenile myoclonic epilepsy (JME)The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C terminus with natriuretic diuretic activity.