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CD55 Polyclonal Antibody, 100ul[BT-AP02035] ADME An isoform lacking exon 6

SKU: 65539380630

4.5
SEK141.00 SEK174.00

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CD55 Polyclonal Antibody, 100ul[BT-AP02035] ADME An isoform lacking exon 6CNOT2 encodes a subunit of the multi component CCR4 NOT complex. The CCR4 NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for CNOT2.

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Description

An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID: 18331714)

This gene encodes a member of the family of secreted protein kinases

|Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair

This protein is related to interleukin 12A (IL12A)

The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex

CD55 Polyclonal Antibody, 100ul[BT-AP02035] ADME An isoform lacking exon 6CNOT2 encodes a subunit of the multi component CCR4 NOT complex. The CCR4 NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for CNOT2.

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