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Apaf-1-ALT Polyclonal Antibody, 100ul Erlenmeyer Flasks This gene is predominantly expressed

SKU: 66064629653

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PLN141.00 PLN164.00

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Apaf-1-ALT Polyclonal Antibody, 100ul Erlenmeyer Flasks This gene is predominantly expressedAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent

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Description

This gene is predominantly expressed in the liver

The encoded protein regulates erythroid gene expression| plays a role in the transcriptional switch of globin gene promoters| and it activates many other cellular and viral gene promoters

This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases

making it ideal for labs looking to increase throughput and save time

The alpha2A subtype inhibited transmitter release at high stimulation frequencies

Apaf-1-ALT Polyclonal Antibody, 100ul Erlenmeyer Flasks This gene is predominantly expressedAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent

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