Stat4 Polyclonal Antibody, 50ul[BT-AP14541] Antibody Humanization This protein binds preferentially to

This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner

which is necessary for homodimerization and for interaction with other leucine zipper proteins

KCNT1 (potassium sodium-activated channel subfamily T member 1) encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways

Gene Ontology (GO) annotations related to this gene include DNA-directed DNA polymerase activity

Three transcript variants encoding two different isoforms have been described

Stat4 Polyclonal Antibody, 50ul[BT-AP14541] Antibody Humanization This protein binds preferentially toThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.