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Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis They form 14-15 kDa proteins

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Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis They form 14-15 kDa proteinsVAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.

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Description

They form 14-15 kDa proteins and are thought to participate in the uptake| intracellular metabolism and/or transport of long-chain fatty acids

It is a constituent of perineuronal nets

which further interacts with the other family members

P311 is expressed at lower levels in hippocampus

The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome

Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis They form 14-15 kDa proteinsVAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.

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