CHD8 Polyclonal Antibody, 100ul Molecular Weight Markers NBPF1 is a member of

NBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder

mucin type) encodes a member of the N-acetylglucosaminyltransferase family

A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma

One protein is a transcriptional repressor

CHD8 Polyclonal Antibody, 100ul Molecular Weight Markers NBPF1 is a member ofThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.