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TEKT1 Rabbit Polyclonal Antibody, 100ul Variant Libraries Overexpression of Baff in mice

SKU: 66481370796

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TEKT1 Rabbit Polyclonal Antibody, 100ul Variant Libraries Overexpression of Baff in miceThis gene product belongs to the tektin family of proteins. Tektins comprise a family of filament forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules indicating that it may play a role in spermatogenesis.

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Description

Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE)

this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking

The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus

including cysteine- and serine- rich regions

which suggests a related but distinct role of this protein

TEKT1 Rabbit Polyclonal Antibody, 100ul Variant Libraries Overexpression of Baff in miceThis gene product belongs to the tektin family of proteins. Tektins comprise a family of filament forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules indicating that it may play a role in spermatogenesis.

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