RUNX1 Polyclonal Antibody, 20ul[BT-AP08059] Immune Cell Preparation The protein (BUB1 mitotic checkpoint

The protein (BUB1 mitotic checkpoint serine/threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C)

Interacts with MAD-MAX heterodimers by binding to MAD

This gene has been linked to both genetic and acquired hypertension

Mutations in this gene cause startle disease

Disruption of CBX2 in mice results in male-to-female gonadal sex reversal

RUNX1 Polyclonal Antibody, 20ul[BT-AP08059] Immune Cell Preparation The protein (BUB1 mitotic checkpointCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three