Elf-4 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation 2000 [PubMed: 11095983])

2000 [PubMed: 11095983])

The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases

The expression of this gene can be induced by nerve growth factor (NGF)

Mutations in NPM1 are associated with acute myeloid leukemia

This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene

Elf-4 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation 2000 [PubMed: 11095983])The E74 like ETS transcription factor 4 encoded by ELF4 is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein have been found for this gene.