PAK gamma(Phospho Ser192) Polyclonal Antibody, 100ul Centrifugal Filter Two major classes of dyneins|

Two major classes of dyneins| axonemal and cytoplasmic| have been identified

This gene is a member of the roadblock dynein light chain family

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

Alternative splicing results in multiple splice variants

which is found in primary NK cells

PAK gamma(Phospho Ser192) Polyclonal Antibody, 100ul Centrifugal Filter Two major classes of dyneins|The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role