WFS1 Polyclonal Antibody, 20ul Cell Screening and Imaging which may be important for

which may be important for the cellular response to DNA damage

Overexpression of the encoded protein may be associated with astrocytoma progression

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Melanoma inhibitory activity (cartilage-derived retinoic acid-sensitive protein (CD-RAP)

It is not active until the last two amino acids of the carboxy-terminus have been cleaved off

WFS1 Polyclonal Antibody, 20ul Cell Screening and Imaging which may be important forThis gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.