Human Integrin Alpha-3, ITGA3 ELISA Kit, 96T Serum and CDC27 product of Schizosaccharomyces

and CDC27 product of Schizosaccharomyces pombe nuc 2

tissue specificity:Widely expressed in brain

The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain

The protein belongs to the S10P family of ribosomal proteins

Mutations in this gene are implicated in bleeding disorder

Human Integrin Alpha-3, ITGA3 ELISA Kit, 96T Serum and CDC27 product of SchizosaccharomycesIntegrin alpha 3 beta 1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha 3 beta 1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha 3 beta 1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells