DNJC3 Polyclonal Antibody, 20ul Centrifuges DCK is clinically important because

DCK is clinically important because of its relationship to drug resistance and sensitivity

both of which are the potent inducers of cell apoptosis

Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection

Three transcript variants encoding different isoforms have been found for AKR1C3

The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity

DNJC3 Polyclonal Antibody, 20ul Centrifuges DCK is clinically important becauseThis gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon induced, dsRNA activated protein kinase (PKR).