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PAR-6Beta Polyclonal Antibody, 50ul Pathway and Network Analysis |Contains 1 BAR domain

SKU: 68450871968

4.3
USD162.00 USD201.00

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PAR-6Beta Polyclonal Antibody, 50ul Pathway and Network Analysis |Contains 1 BAR domainPARD6B is a member of the PAR6 family and encodes a protein with a PSD95 Discs large ZO1 (PDZ) domain, an OPR domain and a semi Cdc42 Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi protein complex.

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Description

|Contains 1 BAR domain

Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner

unlike ubiquitin which targets proteins for degradation

It binds mutliple lipid-containing molecules| including phosphatidylserine| phosphatidylinositol 4-phosphate (PI4P) and oxysterol| and promotes their exchange between the endoplasmic reticulum and the plasma membrane

The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs

PAR-6Beta Polyclonal Antibody, 50ul Pathway and Network Analysis |Contains 1 BAR domainPARD6B is a member of the PAR6 family and encodes a protein with a PSD95 Discs large ZO1 (PDZ) domain, an OPR domain and a semi Cdc42 Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi protein complex.

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