BUB1 Polyclonal Antibody, 100ul[BT-AP01009] Gel & Buffers Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

which are small GTPases involved in protein transport

Negative regulator of ubiquitin like proteins 1 is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies

Chromosome 7 has been linked to Osteogenesis imperfecta

ETV1 encodes a member of the ETS (E twenty-six) family of transcription factors

BUB1 Polyclonal Antibody, 100ul[BT-AP01009] Gel & Buffers Two alternatively spliced transcript variantsBUB1 (BUB1 mitotic checkpoint serine threonine kinase) encodes a serine threonine protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex cyclosome. This protein may also function in the DNA damage response. Mutations in BUB1