OAT1 Polyclonal Antibody, 100ul[BT-AP07394] Low-speed Centrifuges The protein also interacts with

The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1)

and express colocalizing proteins that form a stable hetero-oligomeric complex

This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases

Mutations in this gene have been associated with WHIM (warts

PTM:Phosphorylated on tyrosine residues upon TCR or BCR activation

OAT1 Polyclonal Antibody, 100ul[BT-AP07394] Low-speed Centrifuges The protein also interacts withMultiple cysteine residues are necessary for proper targeting to the plasma membrane.,Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium independent uptake of 2,3 dimercapto 1 propanesulfonic acid (DMPS) (By