Stat5a Polyclonal Antibody, 100ul[BT-AP08639] Centrifugal Filter It contains a 5' CpG

It contains a 5' CpG island that may be a frequent target of hypermethylation| and it may undergo hypermethylation-based silencing in some bladder cancers

May be involved in pre-mRNA processing events

This gene is a candidate gene for autosomal dominant retinitis pigmentosa

and are composed of many polypeptide subunits

This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes

Stat5a Polyclonal Antibody, 100ul[BT-AP08639] Centrifugal Filter It contains a 5' CpGStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.