Rag A/B Polyclonal Antibody, 20ul Filtration Mutations in ACTA1 cause nemaline

Mutations in ACTA1 cause nemaline myopathy type 3

Mutation in this gene has been associated with Naxos disease

VitroGel® COL High Concentration comes with VitroGel® Dilution Solution (Sucrose-free formulation for cells sensitive to the sugar level in the medium) to adjust the final hydrogel strength from 10 to 4000 Pa

The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids

Contributes to cell motility by controlling actin dynamics

Rag A/B Polyclonal Antibody, 20ul Filtration Mutations in ACTA1 cause nemalineHas guanine nucleotide binding activity but undetectable intrinsic GTPase activity. Required for the amino acid induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1 Ran GTPase pathway. May play a direct role in a TNF alpha signaling pathway leading to induction of cell death. May alternatively act as