NFκB-p65(Phospho Ser311) Polyclonal Antibody, 100ul Reservoirs EZH1 is a component of

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al

OTUB2 encodes one of several deubiquitylating enzymes

The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export

and may play a role in regulating the actin cytoskeleton

Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype

NFκB-p65(Phospho Ser311) Polyclonal Antibody, 100ul Reservoirs EZH1 is a component ofNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four