NEIL3 Polyclonal Antibody, 20ul Pipette Filler an autosomal recessive disorder

an autosomal recessive disorder

The encoded protein (deoxyhypusine synthase) catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor

B and C (or elongin B and C)

has both trans-activating and DNA binding activities

Sterilized by irradiation

NEIL3 Polyclonal Antibody, 20ul Pipette Filler an autosomal recessive disorderNEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.