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Numb(Phospho-Ser276) Rabbit Polyclonal Antibody, 50ul Electronic Pipette Upon phosphorylation

SKU: 71004097135

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Numb(Phospho-Ser276) Rabbit Polyclonal Antibody, 50ul Electronic Pipette Upon phosphorylationThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein whose degradation is induced in a proteasome dependent manner by MDM2 is a membrane bound protein that has been shown to associate with EPS15 LNX1 and NOTCH1. Alternative splicing results in multiple transcript variants.

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Description

Upon phosphorylation

The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes

q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2| and a t(8

It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin

GO annotations related to this gene include poly(A) RNA binding and tRNA binding

Numb(Phospho-Ser276) Rabbit Polyclonal Antibody, 50ul Electronic Pipette Upon phosphorylationThe protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein whose degradation is induced in a proteasome dependent manner by MDM2 is a membrane bound protein that has been shown to associate with EPS15 LNX1 and NOTCH1. Alternative splicing results in multiple transcript variants.

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