SphK2(Phospho Thr614) Polyclonal Antibody, 50ul Endonucleases & Exonucleases Defects in this gene are
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SphK2(Phospho Thr614) Polyclonal Antibody, 50ul Endonucleases & Exonucleases Defects in this gene areThis gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1 phosphate. Sphingosine 1 phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced
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