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LOXL2 Polyclonal Antibody, 20ul Transporters Widely expressed in myeloid leukemia

SKU: 71088461792

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LOXL2 Polyclonal Antibody, 20ul Transporters Widely expressed in myeloid leukemiaThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain

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Description

Widely expressed in myeloid leukemia cell lines

Required for the fusion of plasma membranes and early endosomes

and a conserved ACAD domain at the C-terminus

The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha

dephosphorylated KSR1 is membrane-associated

LOXL2 Polyclonal Antibody, 20ul Transporters Widely expressed in myeloid leukemiaThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain

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