MED31 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The first exon of this

The first exon of this gene is unrelated to immunoglobulin variable genes

GO annotations related to this gene include guanyl-nucleotide exchange factor activity and cAMP-dependent protein kinase regulator activity

Mutations in this gene are associated with autism spectrum disorders

and recycling

resulting in the conversion of lysine to alpha-aminoadipic semialdehyde

MED31 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The first exon of thisComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II dependent genes. Mediator functions as a bridge to convey information from gene specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with