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Phospho-BRCA2 (S3291) Polyclonal Antibody, 20ul Pipette Holder along with cyclin H and

SKU: 7139571076

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Phospho-BRCA2 (S3291) Polyclonal Antibody, 20ul Pipette Holder along with cyclin H andInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is

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Description

along with cyclin H and CDK7

Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia

Through the interaction with ILK

The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa

compared to isoform a

Phospho-BRCA2 (S3291) Polyclonal Antibody, 20ul Pipette Holder along with cyclin H andInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is

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