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PLUNC Polyclonal Antibody, 20ul High Speed Micro-Centrifuges Alternatively spliced transcript variants encoding

SKU: 71620956893

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PLUNC Polyclonal Antibody, 20ul High Speed Micro-Centrifuges Alternatively spliced transcript variants encodingBPIFA1 (BPI fold containing family A member 1) is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis

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Description

Alternatively spliced transcript variants encoding different isoforms exist

Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20

Marked reduction in this protein has been observed in association with Alzheimer's disease

NOC3L (NOC3 Like DNA Replication Regulator) is a Protein Coding gene

tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity

PLUNC Polyclonal Antibody, 20ul High Speed Micro-Centrifuges Alternatively spliced transcript variants encodingBPIFA1 (BPI fold containing family A member 1) is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis

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