GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification As a member of the

As a member of the endoplasmic reticulum protein family the encoded protein contains a Lys-Asp-Glu-Leu or KDEL motif located at the extreme C-terminus which prevents all endoplasmic reticulum resident proteins from being secreted

all variants encode the same N-terminus

which has 77% amino acid sequence identity with mouse subunit VIc

Multiple 5' alternatively spliced variants

but may not have lyase activity

GNAO Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification As a member of theThe protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G protein signal transducing complex. Defects in this gene are a cause of early onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.