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KIF20A Polyclonal Antibody, 50ul Human Genome Knockout Libraries RRS1 (Ribosome Biogenesis Regulator Homolog)

SKU: 72334606053

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KIF20A Polyclonal Antibody, 50ul Human Genome Knockout Libraries RRS1 (Ribosome Biogenesis Regulator Homolog)Mitotic kinesin required for chromosome passenger complex (CPC) mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP) bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB7 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end directed motility.

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Description

RRS1 (Ribosome Biogenesis Regulator Homolog) is a Protein Coding gene

this gene shares very high sequence identity with a neighboring gene

Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap

This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2| which appears to be a duplication of the A1 locus

The protein features multiple HEAT repeats

KIF20A Polyclonal Antibody, 50ul Human Genome Knockout Libraries RRS1 (Ribosome Biogenesis Regulator Homolog)Mitotic kinesin required for chromosome passenger complex (CPC) mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP) bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB7 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end directed motility.

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